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More effective training means better muscle preservation, which means more of the weight you lose comes from fat instead of muscle

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Under inflammation, the tryptophan catabolic enzyme, indoleamine 2,3-dioxygenase 1 (IDO1), is induced and that catalyzes the breakdown to Trp to N-formyl kynurenine, which is converted into a more stable metabolite, Kynurenine (KYN), and other downstream bioactive catabolites with profound immunomodulatory effects 49,50,51