[20] The medication may be useful in selected patients with coexisting depression, smoking cessation goals, or alcohol-use concerns, but it is contraindicated in uncontrolled hypertension, seizure disorder, eating disorders such as anorexia nervosa or bulimia nervosa, chronic opioid use, abrupt discontinuation of alcohol or sedatives, use of other bupropion-containing products, and monoamine oxidase inhibitor use within 14 days
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A vial appearing to have little or no vacuum does not indicate contamination, degradation, loss of purity, or compromised integrity