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Maintenance Therapy : For ongoing maintenance, a monthly injection of 1 mg (1000 g) is generally sufficient to maintain adequate vitamin B12 levels in most adults
Patients on Metformin : Patients with type 2 diabetes treated with metformin may experience reduced vitamin B12 absorption
This makes it especially valuable for patients recovering from surgery or extensive injuries who want to regain full range of motion
The dosage chart presented here provides a framework, but the clinical nuances, specifically the titration pace, the dose ceiling, the choice of synergistic agents, and the biomarker monitoring schedule, should be individualized by a physician familiar with both the patient's metabolic history and the evolving evidence base for mitochondrial peptide therapy
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