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immune dysregulation has been linked to ME/CFS patients (201, 255) ( Table 2 ) ( Figure 11 ), it is possible that infectious organisms result in chronic symptoms by interfering with host gene expression, immunity, and metabolism (294, 486)

PLoS ONE 15(6):e0234297 Chaulin AM, Grigorieva JV, Suvorova GN, Duplyakov DV (2021) Experimental modeling of hypothyroidism: principles, methods, several advanced research directions in cardiology

It is documented to stimulate collagen type I and III synthesis by up to 70%, activate fibroblasts, promote angiogenesis, and influence approximately 31% of studied human genes related to tissue repair and antioxidant defense

Similarly, excessive minerals like magnesium or potassium can impact heart rhythm and other organ functions