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Pharmacological determinants in GLP-1RA-Associated cancer risk Differential cancer risk profiles across GLP-1RA subtypes and dosing regimens Existing studies underscore significant differences in the effect of various GLP-1RAs on the risk of specific cancers, such as pancreatic cancer [6,7,8, 26, 27]

These numbers help set realistic expectations: 5 percent body weight loss is often clinically meaningful

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