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Conclusions Nephrotoxicity is associated with significant mortality and morbidity

Rutin : Rutin is a bioflavonoid that possesses antioxidant and anti-inflammatory properties

Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage

benefit: FDA only looked at risk, ignored benefits Off-label use: Doctors prescribe drugs off-label all the time Patient access: People are suffering and need options Regulatory capture: Big Pharma doesn't want cheap peptides competing The problem with these arguments: It's NOT off-label use Off-label only applies to FDA-approved drugs