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doi: 10.1016/j.cmet.2023.01.010 48 ZhuJMaJWangXMaTZhangSWangWet al

PMC 2707813

Some patients report persistent gastrointestinal issues like diarrhea and constipation

In parallel, the bispecific IL-17A/F inhibitor Brivekimig is being assessed in phase 2b trials stratified by draining tunnel burden to address phenotypic and fibrotic heterogeneity [NCT07170917] (Table 2)