fatigue and semaglutide Fatigue: Feeling Weak on Semaglutide Does Semaglutide Make You Tired?

The circadian rhythm governs the sleep-wake cycle, sleep neurons control the transition between wakefulness and sleep, and neurochemical regulation involves various nervous systems and chemical substances ( Sleep is fundamental in regulating the hypothalamic-pituitary-adrenal axis, which is involved in growth hormone (GH) release

This is where Semaglutide enters the picture

Microglial surveillance and response mechanisms in the healthy and damaged brain In healthy brains, microglia continuously sense the alterations in CNS microenvironment by extending and retracting their processes

As the newest addition to incretin-based drugs, tirzepatide harbors the potential to counteract most of the pathogenetic mechanisms underpinning CKD in T2D displaying unprecedented features in terms of glucose and weight lowering, accompanied by promotion of insulin sensitivity, control of SBP, dyslipidemia, and biomarkers of inflammation and endothelial dysfunction