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Comparing the glutathione-scaffold site among a variety of other members of the thioredoxin superfamily also provides an explanation for their disulfide substrate preferences, for example, why glutaredoxins prefer GSSR in contrast to thioredoxins lacking most of the relevant residues (Fig

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Glutathiones detoxifying properties work to cleanse the scalp by neutralising toxins and removing impurities

5.3 Cytokines and macrophage polarization Ferroptosis-driven inflammation promotes the polarization of macrophages toward an M2-like, pro-fibrotic phenotype, largely mediated by cytokines such as TGF- and IL-10 (164)