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GLP-1 drugs are incredibly popular right now, so were seeing side effects at scale

reported that the alpha-linolenic acid metabolism pathway is involved in a plants response to salt stress by regulating the levels of JA [86]

In other words, if you need to use epinephrine, you should do so without hesitation, even if you are on a GLP-1 drug

The liver stores are a bit irrelevant to someone who has PA or a B12 absorption problem though because the mechanism that is used to release them relies on the same mechanism that is used to absorb most dietary B12 so accessing any stores is at best very inefficient