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Methods: This observational retrospective data analysis of patients aged 1865 who completed CHC treatment with a DAA agent between January 2016 and December 2022
Tichansky DS, Boughter JD, Madan AK
Chiang CH, Jaroenlapnopparat A, Colak SC, Yu CC, Xanthavanij N, Wang TH, et al
Practical Application Green tea (EGCG): Catechins show DPP-4 inhibitory activity in vitro Turmeric (curcumin): Demonstrates competitive DPP-4 inhibition Berberine: Reduces DPP-4 expression in laboratory studies Cinnamon extract: Shows modest DPP-4 inhibitory effects Ginger: Contains compounds with DPP-4 inhibitory potential Olive leaf extract: Polyphenols demonstrate DPP-4 modulation Green tea: 3-4 cups daily, brewed at 160-180F for 2-3 minutes Turmeric: 500-1000mg curcumin with black pepper (enhances absorption) Cinnamon: 1-2 teaspoons daily, preferably Ceylon variety Berberine: 500mg 2-3x daily (consult healthcare provider first) Important: Natural DPP-4 inhibition is modest compared to pharmaceuticals
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