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Tumor Incidence and Carcinogenesis Models In selected mouse and rat carcinogenesis models, long-term Epitalon administration correlated with lower tumor incidence, reduced tumor multiplicity, and smaller tumor size in certain genetic backgrounds

For the heart rate, at time points 0 and 10 min after administration there were no significant differences between the groups, while later on there were significant differences between Mel and Dex groups: patients receiving Dex by any route of administration had lower heart frequencies (after 10 and 60 min, p = 0.003

Copper accumulation concerns with long-term use require monitoring

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