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Compound 23 displayed moderate antihyperglycemic activity compared to sitagliptin and showed improvements in insulin resistance reversal and antidyslipidemic properties

Growing Use Cases: Recent clinical trials have shown that GLP-1RAs can also support reducing cardiovascular risk and heart failure-related symptoms and slow down the progression of kidney diseases

Chills are listed under the incidence not known category of side effects by the Mayo Clinic, indicating this effect has been observed, but its frequency is not well established

For terminal studies, mice were sacrificed by CO 2 inhalation, and blood was obtained by CP