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NDP-MSH treatment significantly altered the expression of various transcripts, including chemokines, receptors, and cell cycle mediators, influencing critical signaling pathways like the interleukin-6 (IL-6)/signal transducer and activator of transcription (STAT)/suppressor of cytokine signaling (SOCS) axis
In adults and older children, the total volume used should also stay within safe limits animal studies suggest up to about 30 mL (the full vial) can be given to an adult without benzyl-alcohol toxicity, but one should still use only the amount needed and discard the rest if sterility is lost
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