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SKU: 32038523615

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Description

Atrial fibrillation in adults: Use of oral anticoagulants

E., Cao, X., Streutker, C

Although mouse and human XDH has some functional similarities, species differences in base/amino acid sequences and protein spatial conformation mean that innovative, highly selective small molecule inhibitors or small nucleic acid drugs designed against human XDH often face "acclimatization" issues in wild-type mice, resulting in significantly compromised binding affinity or efficacy