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During the entire experiment, the mice were housed under rigorously controlled conditions, including a temperature of 23C 2C, a relative humidity of 45% 5%, and a consistent 12-hour light/dark cycle
Rosenberger, C
FOXO4-DRI Studies on Heart-Related Mechanisms Declining proteasome activity over time has been associated with protein accumulation and impaired cardiac tissue maintenance
Accordingly, resmetirom, a recently FDA- and EMA-approved, oral, liver-directed, thyroid hormone receptor beta-selective agonist for treating biopsy-proven MASH with advanced fibrosis, has been shown to restore mitochondrial performance [18]
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