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During necrosis, excessive Ca 2+ inflow causes mitochondrial calcium overload, and ROS destroys lipid, protein, and DNA structures, which jointly lead to disordered ionic equilibrium and mitochondrial dysfunction

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doi: 10.3389/fnins.2026.1836124 Received 22 March 2026 Revised 16 April 2026 Accepted 22 April 2026 Published 08 May 2026 Corrected 28 May 2026 Volume 20 - 2026 Edited by Thamires Naela Cardoso Magalhes, Texas A&M University, United States Reviewed by Shubhendu Singh, Santosh University Santosh Medical College and Hospital, India Alvaro A

Activated charcoal can adsorb certain substances in the digestive tract, which may support normal digestive elimination