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Addison's Disease Hyperpigmentation On Tongue Addison's disease - primary adrenal insufficiency - is one of the most clinically significant causes of tongue hyperpigmentation because the oral finding can be a visible clue that leads directly to a life-changing (and potentially life-saving) diagnosis

While there may be some resistance to the conduction of clinical trials of pharmacological interventions in these clinical populations, the mechanistic profile of GLP-1RAs clearly suggests that these medications may play a role in the treatment of certain specific eating disorders, such as BED

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