semaglutide makes me throw up Can Cause Vomiting? Evidence and Management Why Am I Throwing Up

The GLP-1R affinity of semaglutide (0.38 0.06 nM) is three-fold decreased compared to liraglutide, whereas the albumin affinity is increased

This can be the result of alcohol use while on semaglutide, taking multiple diabetes medications at the same time, or gastrointestinal side effects like excessive vomiting or lack of appetite

The GIP receptor component enhances insulin secretion and may contribute to metabolic effects

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