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It is a risk marker and contributes to the development of glomerulosclerosis and interstitial fibrosis (Kang et al., 2002

thus, while these variables are associated with outcomes, their lack of association with the intervention limits the risk of confounding bias

[20] GSH is also essential for the activation of the immune system to generate robust defense mechanisms against invading pathogens

metformin, sulfonylureas, TZDs, etc.) address only one of the underlying pathophysiology - lowering postprandial glucose levels, but their safety profiles and side effects, such as weight gain and hypoglycemia, may present challenges and limitations in their clinical use