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The distinction between IM and subcutaneous is unlikely to be clinically meaningful given the absence of human pharmacokinetic benchmarks for either route

While MIC b12 dosages are safe for short-term use, there have been some reports of side effects when used over a long period

And to do that all of the other delivery methods that could be used need to be thoroughly evaluated, not only as to their effectiveness in correcting the patients B12 Deficiency, but also in how the patient responds to particular delivery methods

Instead of just altering neurotransmitter levels, it promotes the actual formation of new synaptic connections the wiring that underlies memory, learning, and cognition