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(Those who didnt get the drug got a placebo.) The exercise program involved two group exercise classes per week, including 30 minutes of intervals on an exercise bike, then 15 minutes of circuit training (step-ups, boxing, squats, kettlebells, and so on)

Key considerations when choosing a formulation include: Do not crush modified-release tablets or open capsules unless this is explicitly permitted by the product's SmPC doing so can alter the release profile and may be unsafe

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