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Research found that GBB may greatly increase Nitric Oxide (NO) production in the body

How would benefit, no benefit or harm be measured

Shanmugasundaram, K., et al

Cigna's list is unusually generous: "hypertension, type 2 diabetes, dyslipidemia, obstructive sleep apnea, cardiovascular disease, knee osteoarthritis, asthma, chronic obstructive pulmonary disease, metabolic dysfunction-associated steatotic liver disease/non-alcoholic fatty liver disease, polycystic ovarian syndrome, or coronary artery disease." The medication is used "concomitantly with behavioral modification and a reduced-calorie diet." Two details work in your favor