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But pregnancy represents a situation where this particular tool needs to be set aside, even though the underlying condition (obesity) would benefit from continued treatment

Older glucose lowering therapies demonstrated efficacy with respect to achieving glycemic targets but lacked benefits for hard kidney or cardiovascular (CV) outcomes [1]

To ascertain whether plasma and liver FGF21 could act on endocrine pancreas, we analysed the single-cell RNA sequencing data of in vitro differentiation of beta cells [24] (available in the public database GSE114412)

We have previously postulated that these kinds of fatty acid compositional changes could be associated with a preferential stimulation by L-carnitine of saturated fatty acid breakdown in peripheral tissues due to the specificity of the transesterifying enzymes of mitochondrial outer membranes 15