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ET: This article was updated with a statement from a Lilly spokesperson

IKr Delayed ventricular repolarization ECG Prolonged QT interval Increased susceptibility to malignant ventricular arrhythmias The Pharmacokinetic Trigger: CYP3A4 Inhibition Under normal circumstances, Terfenadine is rapidly metabolized by CYP3A4 into its active, non-cardiotoxic metabolite

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