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Wegovy and other GLP-1s are most commonly known for their gastrointestinal side effects, but Wegovy can also cause headaches in some people

Nevertheless, the expression of these NKG2D ligands open the way to use CAR-T cell therapy based on the recognition of these molecules overexpressed on the cell surface of senescent cells

Muscle and bone loss Rapid weight reduction from (but not limited to) GLP-1 use frequently leads to loss of both fat and muscle mass [62,63]

Clinical Evidence and Ongoing Trials A 2023 Phase 2 trial in the New England Journal of Medicine reported approximately 24% mean body weight reduction at 48 weeks with the 12 mg dose