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+ - NNMT has a crucial role in cellular invasion via activating PI3K/Akt/SP1/MMP-2 pathway in clear cell renal cell carcinoma (ccRCC)

Additionally, it has been used in the treatment of depression and other mood disorders due to its ability to enhance neurotransmitter function

4 In another study evaluating topical glutathiones role on UV-induced erythema, Grandi et al 9 found that subjects pre-treated with S-acyl glutathione 2% cream, a linoleic acid pre-conjugate, had a significantly lower minimal erythema dose compared to placebo, indicating UV protective properties ( p =0.0003)