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214 This process is performed in repeated cycles, each of which removes a two-carbon acetyl-coA from the acyl-CoA via four enzymes, the enoyl-CoA hydratase, ketoacyl-CoA thiolase, acyl-CoA dehydrogenase (ACADs) and hydroxyacyl-CoA dehydrogenase (HADH)

Mice were pretreated with lidocaine (Accord Healthcare) at the site of incision, anaesthetized with isoflurane and fixed in a stereotaxic instrument

MD trajectories are available at Source data are provided with this paper

The DHSC issued a national patient safety alert for GLP-1 RAs on 2 January 2024, which stated that the shortage resulted from increased demand for both licensed and off-label indications