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Protect the joint by avoiding aggravating activities for the first two to three days

Gradual Increase : After two to four weeks, if well-tolerated, the frequency of application can be gradually increased to nightly use

Triglycerides Triglycerides are storage lipids that have a critical role in metabolism and energy utilization

While the reduction in disease progression was correlated to the modulation of macrophage activity, in contrast to the administration of the ES products, FhHDM-1-mediated protection was associated with the reduced ability of macrophages to respond to pro-inflammatory ligands, suggesting the regulation of an M1-like phenotype, and indicating multiple mechanisms mediating an overall switch from a predominance of pro-inflammatory to anti-inflammatory macrophages (104)