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In rodent models, a notable concern has been the observation of C-cell hyperplasia and medullary thyroid carcinomas associated with chronic administration of GLP-1 receptor agonists

Results from the FLOW trial, which assessed semaglutide (Ozempic, Novo Nordisk) in adults with type 2 diabetes and CKD, were first presented at the European Renal Association Congress and published in The New England Journal of Medicine in May

Side-by-side comparison v3.0 transparency score NexLife: 94/100 (6 of 6 pillars) Eden Health: 72/100 (1 of 6 pillars) Drugs offered NexLife: Compounded semaglutide + tirzepatide Eden Health: Semaglutide + Tirzepatide Pricing model NexLife: Flat $145/mo sema, $186/mo tirz (12-mo plan, dose-independent) Eden Health: $149-$229/mo Clinical model NexLife: MD/DO-supervised, synchronous + async Eden Health: Compounded with hormone and metabolic add-ons Pharmacy NexLife: Named 503A & 503B partners Eden Health: 503A partner States covered NexLife: Availability varies by state + DC Eden Health: Varies Labs included NexLife: Yes included in monthly Eden Health: Add-on or not included Coaching NexLife: 1:1 fitness coaching + personalized nutrition included Eden Health: Varies by plan Financing NexLife: Klarna and Afterpay accepted Eden Health: Standard card payment Regulatory clarity NexLife: Pre-Rx written disclosure that compounded sema/tirz are not FDA-approved Eden Health: Varies Where Eden Health wins Cross-sells hormone optimization and metabolic peptides

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