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CEO/Chair, Council of Experts Topics The Basics Management The FutureScience The FuturePutting It Together Topics The Basics Management The FutureScience The FuturePutting It Together Key Elements of Science & Standards Division: Organization Flow Drivers for Change Increase/improve interface between different parts of USP Increase efficiency on work flow within SSD External to USP Internal within USP Expert Committees were recently restructured to manage monographs and reference standards To make project ownership for each product clear (single point of accountability in the context of the team) Maximize capacity of our work load (identify constraints and provide solutions) Drivers For Change: Outcomes Products (monographs, reference materials) to our customers are synchronized and reference standards are available as early as possible There is a portfolio owner for each segment of the portfolio for Small Molecules, Biologics, Excipients, Dietary Supplements, Food Ingredients, General Chapters/Pharmacists Pharmacopeia, Healthcare Quality Standards A uniform criteria for priority setting

If levels of oxalate in the glomerular filtrate increase (hyperoxaluria) it can chelate Ca 2+ ions forming the insoluble compound, calcium oxalate