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This kit has not been compared with similar kits from other manufacturers or products that detect the same target object using different methods, so inconsistent test results cannot be ruled out

PI3K, phosphoinositide 3-kinase

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At the level of precursor lesions such as nevi, the initial mutagenic events triggering the neoplastic transformation are represented by several mutations which lead to the activation of the MAPK pathway (such as BRAF V600E), while at an intermediate stage of tumour progression, NRAS and additional driver mutations are seen