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The influence of peptide context on signaling and trafficking of glucagon-like peptide-1 receptor biased agonists

On the other hand a GLP1-ANP axis has been only demonstrated in hypertensive mice, in which GLP-1R activation in the atria leads to ANP secretion and stimulation of natriuresis and vasodilation in the consequence

This review underscores the necessity of early recognition, accurate diagnosis, and tailored interventions to mitigate complications and enhance patient outcomes