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It is not a human medicinal product, for aesthetic applications it is used in topical preparations

Other cellular factors such as oxidative stress and inflammation can also negatively impact systemic and cerebral endothelial function by damaging endothelial cells (Shaito et al., 2022) and reducing nitric oxide bioavailability (Gryglewski et al., 1986)

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Anokhi Mehta, MD, Virtua pain medicine specialist, explains the symptoms and treatments available