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Immunostained cells were imaged on an SP8 confocal microscope and acquisition software (LAS X, Leica Microsystems)

Nervous system symptoms like depression, anxiety, and memory problems in severe deficiency

Less delayed-onset muscle soreness, faster return to baseline strength between hard workouts, and reduced stiffness in nagging joints

Where the benefit is included, prior authorization is required: typically BMI 30 or higher, or BMI 27 or higher with a weight-related comorbidity (hypertension, type 2 diabetes, dyslipidemia, or obstructive sleep apnea), plus documented lifestyle program participation and weight-loss maintenance for renewal