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Samuels, a professor at the Oregon Clinical and Translational Research Institute, stated: It is a common clinical observation that some otherwise healthy patients with hypothyroidism continue to complain of fatigue, poor mood, inability to concentrate, and vague cognitive difficulties (often described as brain fog) despite normal TSH levels. [5] 2

The study's core methodology involves a combination of in vivo mouse models, human data analysis, and in vitro organoid experiments to investigate how intestinal inflammation affects GLP-1+ cell numbers and function