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Third-party testing provides assurance that the product contains what's on the label

3436 Another meta-analysis of 49 randomized controlled trials found that thiazolidinediones (especially pioglitazone [Actos]) improved steatosis and inflammation but were associated with a weight increase of 4.5 to 11 lb (2 to 5 kg) in 66% to 75% of patients and edema in 4% to 10% of patients

Food and Drug Administration for use in adults 18 and older who have a body mass index (BMI) of 25 or more