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Entry of fatty acids into the mitochondria relies on carnitine palmitoyltransferase 1 (CPT1) situated in the outer mitochondrial membrane [80], but as the mitochondria lack the ability to oxidize very long chain fatty acids [79], these are preferably metabolized via peroxisomal -oxidation

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Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist