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Description

The difference in mechanism explains why clinical trials show semaglutide users lose 10-15% of body weight, while supplement studies rarely exceed 3-5% average reductions

There are additional concerns about stomach paralysis and malnutrition because of extreme appetite suppression

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Several GLP-1 and dual GIP/GLP-1 receptor agonists have been developed to harness these pharmacological effects in the treatment of type 2 diabetes, with some demonstrating robust effectiveness in weight management and prevention of cardiovascular diseases