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IGF1 stimulates greater muscle hypertrophy in the absence of myostatin in male mice

10.18632/aging.204769 135 SunG.WuY.LiJ.YangM.XuH.LiY.et al (2025)

Nutrition Strategies That Complement GLP-1 Therapy GLP-1 medications reduce appetite, making strategic nutrition essential for muscle preservation.Working with your healthcare provider, we recommend: Optimal protein intake of approximately 0.5-0.9 grams per pound of body weight daily, with particular emphasis on: Distribution throughout the day (20-30g per meal) Complete protein sources containing essential amino acids Protein-dense options that provide maximal nutrition in smaller volumes Strategic mealtiming to support muscle protein synthesis, particularly: Post-exercise nutrition within 1-2 hours of resistance training Evening protein intake to support overnight muscle maintenance Supportive micronutrients critical for neuromuscular function, including vitamin D, magnesium, calcium, and B-complex vitamins