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Key mechanisms through which weight loss may influence menstruation include: Hormonal rebalancing: Rapid weight loss can temporarily alter the balance of reproductive hormones, including oestrogen, progesterone, luteinising hormone (LH), and follicle-stimulating hormone (FSH)

D57 (CTR) and D254 (G), were predicted protonated, however, visual inspection did not support this prediction because of their solvent-exposed location and, therefore, were modelled in the anionic side chain form

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Metal-based systems (MnO, Cu 2 , Fe 3 ) deplete GSH and generate ROS, with imaging potential, though metal toxicity and accumulation are concerns