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Glutathione transferases (GSTs) help protect cells from oxidative stress and toxic molecules Glutathione peroxidase reduces organic hydroperoxides Glutathione reductase reduces oxidized glutathione back to its active form If glutathione is deficient, the body cannot properly eliminate toxins
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First, the sulfonation reaction saturates and that allows more NAPQI to accumulate ([7, 24]) and second, the increased amount of NAPQI exhausts the liver stores of reduced glutathione (GSH)[6] as well as the livers capacity to synthesize new GSH
doi: 10.3892/ijmm.2014.1994 4 BakshiM
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