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And, GLP-1(7-36)amide significantly prevented LPS-, IL-1-, H2O2-induced impairment in synaptic functions of hippocampal CA1 region (219)

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Undermethylation is evaluated with symptoms, whole-blood histamine and other biochemical markers

Pre-treatment considerations should include: Disease activity assessment : GLP-1 agonists should ideally be initiated when Crohn's disease is in remission or well-controlled, as distinguishing medication side effects from disease flare becomes challenging during active inflammation Nutritional status evaluation : Patients with Crohn's disease may already have compromised nutritional status