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The treatment policy estimand included all study participants randomly assigned to each treatment, using data regardless of discontinuation of study medications and/or use of additional blood glucose lowering medications during the trial (thereby reflecting the intention-to-treat principle)
2) Avoid:Strong acids (e.g., AHAs, high-dose vitamin C) or chelators (e.g., EDTA), which may destabilize the copper-peptide complex.
Weeks 3-4: 1 to 1.5 mg daily
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