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10 M cisplatin (CIS) and 100 mM D-methionine (bottom left image) and 10 M cisplatin (CIS) and 0.1 mM D-methionine (bottom right image)

doi: 10.3390/nu15092131 73 CritchleyHODBabayevEBulunSEClarkSGarcia-GrauIGregersenPKet al

In line with previous results obtained in rodent neuronal cultures 43 , we found that the administration of lactate in a concentration range of 520 mM (which are relatively high as compared to physiological ones 19 ) caused an immediate drop in the electrophysiological activity of hiPSCs-derived neuronal networks, in a concentration-dependent manner