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Abstract Diabetes mellitus is one of the most important threats to human health in the twenty-first century

In contrast, studies involving conditions such as schizophrenia, osteoarthritis, migraine, and functional gastrointestinal disorders were grouped under Non-metabolic chronic conditions, due to their distinct primary pathophysiological pathways, which do not centrally involve metabolic dysregulation

Compounds that inhibit the action of MAO exhibited beneficial effects in the treatment of clinical depression, even when tricyclic antidepressants are ineffective

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