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People with insulin resistance often have blunted GLP-1 responses to meals, which partially explains why they struggle with persistent hunger even after eating adequate calories

By aiding first-phase insulin release (through rapid Ca 2+ influx via channels) and possibly protecting -cells from glucotoxicity (through reduced oxidative stress and Ca 2+ stress), cinnamon helps restore proper insulin signaling needed for homeostasis

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For these reasons, most medical guidelines recommend postponing pharmacological weight loss interventions until after breastfeeding concludes, unless maternal health risks make immediate intervention necessary and appropriate medical oversight is in place