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4 In recent years, there has been a significant increase in attention, research, and clinical advancements delving into the intricate mechanisms underlying the effects of GLP-1 agonists in various disorders

(12) The growing number of orthopedic patients with obesity thus underscores an urgent need for interventions that target both weight reduction and metabolic optimization, offering the potential to improve overall surgical safety and long-term musculoskeletal health

Another key driver is the diversification of therapeutic area, i.e., obesity and management of cardio metabolic risk to expand market opportunity