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Metabolic functions of gut microbes associate with efficacy of tumor necrosis factor antagonists in patients with inflammatory bowel diseases

278 A clinical study revealed elevated serum levels of TNF- and its soluble receptors in patients with AP, 279 although the levels of TNF- or soluble TNF- alone have limited predictive value for early septic shock in SAP patients

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Clinically, GLP-1-based therapies offer the additional advantage of established cardiovascular protection and renal benefits, making them particularly attractive for the large proportion of MASLD patients with comorbid cardiovascular disease or type 2 diabetes