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This article summarises the position reached with the GLP-1 RAs and reviews the developing field of unimolecular co-agonists that act not only on the GLP-1 receptor, but on other receptors, notably glucose-dependent insulotropic polypeptide (GIP) and glucagon receptors, with the aim of further improving glycaemic control and weight reduction

Content may require purchase if you do not have access.) Article purchase Temporarily unavailable References McIntyre, RS, Kwan, ATH, Rosenblat, JD, Teopiz, KM, Mansur, RB

Five impact areas are identified: glycemic profile, inflammation, oxidative stress, lipid profile, and hormonal profile, each linked to metabolic and endocrine alterations characteristic of PCOS

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